Number of tRNA molecules per cell

Range ~375,000 Molecules/cell
Organism Bacteria Escherichia coli
Reference Mackie GA. RNase E: at the interface of bacterial RNA processing and decay. Nat Rev Microbiol. 2012 Dec 14 11(1):45-57. doi: 10.1038/nrmicro2930. p.51 box 2PubMed ID23241849
Primary Source Dong H, Nilsson L, Kurland CG. Co-variation of tRNA abundance and codon usage in Escherichia coli at different growth rates. J Mol Biol. 1996 Aug 2 260(5):649-63.PubMed ID8709146
Comments "In a culture of E.coli k12 that grows with a doubling time of ~30 min, there will be approximately 50,000 ribosomes, 375,000 tRNAs (primary source) (7.5 per ribosome) and perhaps a single to at most ten copies of each of the ~2,000 mRNAs per cell." Note-value wasn't located in primary source
Entered by Uri M
ID 108611