Gradient of morphogen that can be detected from one end of cell to another

Value 2 %
Organism Various
Reference Day SJ, Lawrence PA. Measuring dimensions: the regulation of size and shape. Development. 2000 Jul127(14):2977-87. p.2983 right column bottom paragraphPubMed ID10862736
Comments Dictyostelium and leucocytes have been studied and it seems that such cells can compare the local concentration perceived at (a minimum of) two sites on the cell surface that are a fixed distance apart. They can detect differences in concentration of as little as 2% from one end of the cell to another, even in widely varying ambient concentrations (Zigmund, 1981 Parent et al., 1998 Jin et al, 2000 Servant et al, 2000 reviewed in Parent and Devreotes, 1999).
Entered by Uri M
ID 107047