Diffusion coefficient for lac O sites in spermatocyte nucleus

Range 0.004-0.013 µm^2/sec
Organism Fruit fly Drosophila melanogaster
Reference Vazquez J, Belmont AS, Sedat JW. Multiple regimes of constrained chromosome motion are regulated in the interphase Drosophila nucleus. Curr Biol. 2001 Aug 2111(16):1227-39.PubMed ID11525737
Method Chromosome motion was tracked in Drosophila spermatocyte nuclei by 3D fluorescence microscopy. The Lac repressor/lac operator system was used to label specific chromosomal sites in live tissues, allowing extended observation of chromatin motion in different cell cycle stages.
Comments 0.004 µm^2/sec for late G2 phase, 0.013 µm^2/sec for early G2 phase
Entered by Uri M
ID 104289