Time for red blood cell to lose biconcave shape following hemolysis

Range 5-10 Days
Organism Human Homo sapiens
Reference Wagner KR, Dwyer BE. Hematoma removal, heme, and heme oxygenase following hemorrhagic stroke. Ann N Y Acad Sci. 2004 Mar1012:237-51PubMed ID15105270
Primary Source Darrow VC, Alvord EC Jr, Mack LA, Hodson WA. Histologic evolution of the reactions to hemorrhage in the premature human infant's brain. A combined ultrasound and autopsy study and a comparison with the reaction in adults. Am J Pathol. 1988 Jan130(1):44-58PubMed ID3276212
Method With the development and routine use of real-time ultrasound scanning, it has been possible to collect 20 autopsy cases of infants in whom the ultrasound scan was first normal and then showed evidence of subependymal/intraventricular hemorrhage (SEH/IVH). Analysis of these cases with known postnatal origin of the hemorrhage permitted the development for the first time of a time scale to characterize the temporal evolution of the histopathologic reactions to hemorrhage in the premature human brain.
Entered by Uri M
ID 104199