Results
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Property | Organism | Value | Units | ID | Details |
---|---|---|---|---|---|
Fraction of variance in protein fitness that can be explained by thermostability | Unspecified | 18 | % | 110453 | Firnberg E, Labonte JW... |
Free energy of protein-protein association | Mammals | Table - link | N/A | 107884 | Chothia C, Janin J. ... |
Smoothed histograms (logarithmically spaced bins) of the time distributions for protein folding, translation, and diffusion compared to a range of reaction rates | Bacteria Escherichia coli | Figure link - link | Seconds | 107053 | Dill KA, Ghosh K, Schmit... |
Refolding time of 'fast refolding' lysozyme | Chicken Gallus gallus | 50 | msec | 104602 | Thirumalai D, Klimov... |
Refolding time of 'slow refolding' lysozyme | Chicken Gallus gallus | 400 | msec | 104603 | Thirumalai D, Klimov... |
Number of proteins that are part of the proteostasis network (PN) (total of ~1,300 different proteins) | Mammals | proteins involved in: protein biogenesis ~400: conformational maintenance ~300: degradation ~700 | different proteins | 113352 | Kim YE, Hipp MS, Bracher A... |
Fraction of newly synthesized polypeptides that chaperonins interact with | Various | in bacteria and archaea 10% - 15%: in eukarya 5% - 10% | % | 113350 | Kim YE, Hipp MS, Bracher A... |
Unfolding distance (Xu) of I27, 27th immunoglobulin-like domain of human cardiac titin | Human Homo sapiens | 0.25 | nm | 114334 | Ainavarapu SR et al.... |
Overall diameter of heat shock protein DegP | Bacteria Escherichia coli | ~20 | nm | 114124 | De Geyter J et al., Protein... |
Fraction of total protein mass that is cytosolic chaperone HSPA8 (HSC70) | Eukaryotes | ≤1 | % | 111538 | Finka A, Sood V, Quadroni M... |
Number of ATPs consumed by one Hsp70 to effectively unfold a single misfolded protein into an intermediate in vitro | Bacteria Escherichia coli | 5 | ATP | 113282 | Sharma SK, De los Rios P... |
Percent of proteins that can fold without chaperones | bacteria | 70 | % | 109698 | Hartl, F. U., Bracher... |
Average protein lengths | Bacteria Escherichia coli | Essential genes 343.2: nonessential genes 329 Table - link | Amino acids | 108985 | Gong X, Fan S, Bilderbeck A... |
Fraction of actively translated proteins that are bound to Hsp70 SSB | Budding yeast Saccharomyces cerevisiae | 65 | % | 113365 | Willmund et al., The... |
Enzymes for which kcat/KM is close to the diffusion-controlled limit | Generic | Table - link | N/A | 105087 | Stryer et al, Biochemistry... |
Average size of endogenous E. coli cytosolic protein | Bacteria Escherichia coli | 300 | amino acids | 100017 | Brandt F, Etchells SA... |
Fraction of total protein mass that are members of the chaperome network in unstressed cells | Human Homo sapiens | ≤10 | % | 111537 | Finka A, Sood V, Quadroni M... |
The protein economy-vital statistics-copies per cell and rates of action (probably for HeLa cell) | Human Homo sapiens | Table - link | N/A | 113834 | Yewdell JW. Not such... |
Fraction of disordered proteins in proteome | Various | bacteria ~5%: higher eukaryotes ~30-50 | % | 116234 | Theillet FX et al., ... |
Fraction of nascent polypeptides associated with Hsp70 SSB | Budding yeast Saccharomyces cerevisiae | ~45 | % | 113361 | Wang F, Durfee LA, Huibregtse... |