The turnover of nuclear DNA-like RNA in HeLa cells

J Cell Biol. 1968 Oct;39(1):112-8. doi: 10.1083/jcb.39.1.112.

Abstract

The subcellular distribution of various types of RNA in HeLa cells is described. In addition, the relative rate of synthesis of the major classes of nuclear RNA has been determined. From these experiments it can be deduced that the heterogeneous nuclear RNA fraction is rapidly synthesized and degraded within the cell nucleus.

MeSH terms

  • Carbon Isotopes
  • Cell Nucleus / metabolism*
  • DNA, Neoplasm / metabolism*
  • HeLa Cells / metabolism*
  • Humans
  • Phosphorus Isotopes
  • RNA, Neoplasm / biosynthesis
  • RNA, Neoplasm / metabolism*
  • Uridine / metabolism

Substances

  • Carbon Isotopes
  • DNA, Neoplasm
  • Phosphorus Isotopes
  • RNA, Neoplasm
  • Uridine