Abstract
Diffusion coefficients (D) of a lipid probe and labeled proteins on L-6 myoblast membranes have been measured giving D(protein) approximately 2 X 10(-10) square centimeter per second and D (lipid probe) approximately 9 X 10(-9) square centimeter per second. Some of the membrane proteins are immobile, but the lipid probe diffuses freely over macroscopic distances. Cytochalasin B slows protein but not lipid probe diffusion.
Publication types
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Research Support, U.S. Gov't, Non-P.H.S.
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Azides / pharmacology
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Cell Line
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Cell Membrane / ultrastructure
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Colchicine / pharmacology
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Cytochalasin B / pharmacology
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Cytoskeleton / physiology
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Diffusion
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In Vitro Techniques
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Membrane Lipids / physiology*
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Membrane Proteins / physiology*
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Spectrometry, Fluorescence
Substances
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Azides
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Membrane Lipids
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Membrane Proteins
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Cytochalasin B
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Colchicine