Abstract
The biochemical information on the basic cellular determinants of the human red cell has been compiled into a comprehensive model of the red cell metabolic machinery. This model gives a consistent interpretation--both qualitative and quantitative--of the experimental findings. The predicted steady states and the dynamic states of the model are compared with the experimental findings, and the utility of this model is demonstrated.
Publication types
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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2,3-Diphosphoglycerate
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Adenosine Triphosphate / metabolism
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Biological Transport, Active
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Ca(2+) Mg(2+)-ATPase / metabolism
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Diphosphoglyceric Acids / metabolism
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Erythrocytes / enzymology
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Erythrocytes / metabolism*
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Humans
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Hydrogen-Ion Concentration
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Kinetics
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Models, Biological
Substances
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Diphosphoglyceric Acids
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2,3-Diphosphoglycerate
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Adenosine Triphosphate
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Ca(2+) Mg(2+)-ATPase