Metabolic dynamics in the human red cell. Part IV--Data prediction and some model computations

J Theor Biol. 1990 Jan 9;142(1):69-85. doi: 10.1016/s0022-5193(05)80013-x.

Abstract

The biochemical information on the basic cellular determinants of the human red cell has been compiled into a comprehensive model of the red cell metabolic machinery. This model gives a consistent interpretation--both qualitative and quantitative--of the experimental findings. The predicted steady states and the dynamic states of the model are compared with the experimental findings, and the utility of this model is demonstrated.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • 2,3-Diphosphoglycerate
  • Adenosine Triphosphate / metabolism
  • Biological Transport, Active
  • Ca(2+) Mg(2+)-ATPase / metabolism
  • Diphosphoglyceric Acids / metabolism
  • Erythrocytes / enzymology
  • Erythrocytes / metabolism*
  • Humans
  • Hydrogen-Ion Concentration
  • Kinetics
  • Models, Biological

Substances

  • Diphosphoglyceric Acids
  • 2,3-Diphosphoglycerate
  • Adenosine Triphosphate
  • Ca(2+) Mg(2+)-ATPase