Effect of vitrification and thawing on human oocyte ATP concentration

Fertil Steril. 2011 Apr;95(5):1839-41. doi: 10.1016/j.fertnstert.2010.10.040. Epub 2010 Nov 11.

Abstract

Vitrification/thawing has a significant negative impact on oocyte ATP concentration. However, incubating oocytes up to 180 minutes after thawing allowed oocytes to regain some ATP level.

Publication types

  • Evaluation Study
  • Research Support, N.I.H., Intramural

MeSH terms

  • Adenosine Triphosphate / analysis*
  • Adenosine Triphosphate / metabolism
  • Cell Survival
  • Cells, Cultured
  • Cryopreservation* / methods
  • Female
  • Hot Temperature
  • Humans
  • Mitochondria / metabolism
  • Mitochondria / physiology
  • Oocytes* / chemistry
  • Oocytes* / metabolism
  • Oocytes* / physiology
  • Osmolar Concentration
  • Time Factors

Substances

  • Adenosine Triphosphate