The top genes: on the distance from transcript to function in yeast glycolysis

Curr Opin Microbiol. 2003 Apr;6(2):198-201. doi: 10.1016/s1369-5274(03)00023-7.

Abstract

With its abundant components and extensive study, the glycolytic pathway in the yeast Saccharomyces cerevisiae would appear ideal to obtain and reconcile the 'omes of transcript, protein, metabolite and flux. But to do so is challenging and, as is often the case, close correlation of gene expression and function is elusive, even in this organism.

Publication types

  • Review

MeSH terms

  • Gene Expression Regulation, Fungal
  • Genes, Fungal
  • Glycolysis
  • Models, Genetic
  • Saccharomyces cerevisiae / genetics
  • Saccharomyces cerevisiae / metabolism*
  • Saccharomyces cerevisiae Proteins / biosynthesis*
  • Saccharomyces cerevisiae Proteins / genetics
  • Saccharomyces cerevisiae Proteins / physiology*
  • Transcription, Genetic

Substances

  • Saccharomyces cerevisiae Proteins