The function and synthesis of ribosomes

D L Lafontaine; D Tollervey

doi:10.1038/35080045

The function and synthesis of ribosomes

Nat Rev Mol Cell Biol. 2001 Jul;2(7):514-20. doi: 10.1038/35080045.

Authors

D L Lafontaine¹, D Tollervey

Affiliation

¹ FNRS, Université Libre de Bruxelles, Département de Biologie Moléculaire, IRMW - Campus CERIA, Avenue Emile Gryson 1, B-1070 Brussels, Belgium. denis.lafontaine@ulb.ac.be

PMID: 11433365
DOI: 10.1038/35080045

Abstract

Structural analyses of the large and small ribosomal subunits have allowed us to think about how they work in more detail than ever before. The mechanisms that underlie ribosomal synthesis, translocation and catalysis are now being unravelled, with practical implications for the design of antibiotics.

Publication types

Research Support, Non-U.S. Gov't
Review

MeSH terms

Bacteria / genetics*
Eukaryotic Cells / physiology
Humans
Molecular Structure
Peptidyl Transferases / chemistry
Peptidyl Transferases / metabolism
Protein Biosynthesis / physiology
RNA / metabolism
Ribosomes / metabolism*

Substances

RNA
Peptidyl Transferases