Abstract
Escherichia coli cells infected with T4 phage which are deficient in both nuclear disruption and endonuclease II exhibit a pathway of host DNA degradation which does not occur in cells infected with phage deficient only in endonuclease II. This alternate pathway of host DNA degradation requires T4 endonuclease IV.
Publication types
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Cell Nucleus / metabolism
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Coliphages / enzymology*
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Coliphages / growth & development
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DNA Viruses
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DNA, Bacterial / metabolism*
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Deoxyribonucleases / biosynthesis*
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Endonucleases / metabolism*
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Escherichia coli / metabolism*
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Genes
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Isoenzymes / metabolism*
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Lysogeny
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Microscopy, Electron
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Mutation
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Nucleic Acid Denaturation
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Virus Replication
Substances
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DNA, Bacterial
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Isoenzymes
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Deoxyribonucleases
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Endonucleases