Total number of proteins in HeLa cell

Range ~2E+9 but see comment (from ron milo) that suggests ~10^10 polypeptides/cell
Organism Human Homo sapiens
Reference Finka A, Goloubinoff P. Proteomic data from human cell cultures refine mechanisms of chaperone-mediated protein homeostasis. Cell Stress Chaperones. 2013 Feb 21 p.3 right column bottom paragraphPubMed ID23430704
Primary Source Nagaraj N, Wisniewski JR, Geiger T, Cox J, Kircher M, Kelso J, Pääbo S, Mann M. Deep proteome and transcriptome mapping of a human cancer cell line. Mol Syst Biol. 2011 Nov 8 7: 548. doi: 10.1038/msb.2011.81.PubMed ID22068331
Method Online liquid chromatography coupled to high-resolution MS and MS/MS (mass spectrometry).
Entered by Uri M
ID 109387