Proliferation rate of CD8 T-cells in C57BL/6 mice after virus infection

Range 1-2 1/day
Organism Mouse Mus musculus
Reference De Boer RJ, Homann D, Perelson AS. Different dynamics of CD4+ and CD8+ T cell responses during and after acute lymphocytic choriomeningitis virus infection. J Immunol. 2003 Oct 15 171(8):3928-35. p.3934 left column table IIIPubMed ID14530309
Method The estimates provided here for the CD8+ T cell response to LCMV Armstrong epitopes in C57BL/6 mice are somewhat slower (than in BALB/c mice, BNID 101560), i.e., the time of the peak is at day 8, and the proliferation rate is 1.9 d^-1 for the immunodominant CD8+ responses.
Comments Fit to in vivo data of LCMV infection in C57BL/6 mice. Range given in table III for the 6 epitopes is 1.13-1.92/day and the confidence intervals ((lowest to highest 95% CI) of the six epitopes are 0.98-2.21/day).
Entered by Ben Marks
ID 101561