Total surface area of the lacuno-canalicular system

Value 215 m^2 Range: Table - link m^2
Organism Human Homo sapiens
Reference Buenzli PR, Sims NA. Quantifying the osteocyte network in the human skeleton. Bone. 2015 Jun75: 144-50. doi: 10.1016/j.bone.2015.02.016. abstract, p.146 table 3, p.147 left column 2nd paragraph & p.148 right column 4th paragraphPubMed ID25708054
Primary Source See refs beneath table
Method Abstract:"[Investigators] have used data from recent papers obtained by new imaging techniques, in order to estimate absolute and relative quantities of the human osteocyte network and form a more complete understanding of the extent and nature of this network."
Comments Abstract:"[Investigators] estimate the total length of all osteocytic processes connected end-to-end to be 175,000 km. Furthermore, [they] calculate that the total surface area of the lacuno-canalicular system is 215 m^2." p.147 left column 2nd paragraph:"The average surface area of a human osteocyte lacuna was reported in [ref 31] to be 336.2 µm^2. Multiplying by the total number of osteocyte lacunae (including empty lacunae), this corresponds to a total lacunar surface area (Tt.Lc.S) of 11.8–17.7 m^2 (average of 14.7 m^2). The total surface area of the human lacuno-canalicular network (Tt.LCN.S) is thus 212.4–218.3 m^2 (average of ~215 m^2)." p.148 right column 4th paragraph:"The surface area of the lacuno-canalicular network (Tt.LCN.S) is large, an estimated total of 215 m^2. This is more than that of a healthy adult lung (118 m^2) [primary source 62 beneath table], and much larger than the surface areas of the gastrointestinal tract (32 m^2) [primary source 63 beneath table] and the skin (2 m^2) [primary source 64 beneath table] (Table 3)."
Entered by Uri M
ID 111551