Average peptide half-life

Value 1 hour
Organism Bacteria Staphylococcus aureus
Reference Pai A, You L: Optimal tuning of bacterial sensing potential. Molecular systems biology 2009, 5(286) :286 doi: 10.1038/msb.2009.43. Supplementary Text 2 p.24 top paragraphPubMed ID19584835
Primary Source Horswill AR, Stoodley P, Stewart PS, Parsek MR (2007) The effect of the chemical, biological, and physical environment on quorum sensing in structured microbial communities. Analytical and bioanalytical chemistry 387: 371-380. AND Wright JS, 3rd, Jin R, Novick RP (2005) Transient interference with staphylococcal quorum sensing blocks abscess formation. Proceedings of the National Academy of Sciences of the United States of America 102: 1691-1696.PubMed ID17047948, 15665088
Comments Supplementary Text 2 p.24 top paragraph:"Experimentally observed half-lives are used to estimate peptide degradation rates. If data is unavailable, an average peptide half-life (primary sources) of 1 hr is assumed, giving da= 0.693hr^-1."
Entered by Uri M
ID 112002