Fraction of cardiomyocytes that are binucleated at birth
| Range | ~25 % |
|---|---|
| Organism | Human Homo sapiens |
| Reference | Bergmann O et al., Evidence for cardiomyocyte renewal in humans. Science. 2009 Apr 3 324(5923):98-102. p.100 middle column top paragraphPubMed ID19342590 |
| Primary Source | Olivetti G, Cigola E, Maestri R, Corradi D, Lagrasta C, Gambert SR, Anversa P. Aging, cardiac hypertrophy and ischemic cardiomyopathy do not affect the proportion of mononucleated and multinucleated myocytes in the human heart. J Mol Cell Cardiol. 1996 Jul28(7):1463-77.PubMed ID8841934 |
| Comments | About 25% of cardiomyocytes are binucleated in humans at birth, and this proportion stays constant throughout life (primary source). |
| Entered by | Uri M |
| ID | 107075 |