In vitro residence time for glucocorticoid receptor (GR) to DNA

Value 108 Min
Organism Rat Rattus norvegicus
Reference Perlmann T, Eriksson P, Wrange O. Quantitative analysis of the glucocorticoid receptor-DNA interaction at the mouse mammary tumor virus glucocorticoid response element. J Biol Chem. 1990 Oct 5 265(28):17222-9 p.17225 right column 2nd paragraphPubMed ID2170368
Method The dissociation rate from the Upstream Binding Region (UBR) was measured by adding a 60-fold molar excess of unlabeled GR binding sites over GR sites on the 32P-labeled DNA to a preformed GR•MTVwt complex at time zero.
Comments See BNID 106483, 106484
Entered by Uri M
ID 106485