Increase in premature peptide release at A site of ribosome when there is a single mismatch of codon/anti codon double helix at P site

Value 2 Orders of magnitude
Organism bacteria
Reference Hani S. Zaher and Rachel Green, Fidelity at the Molecular Level: Lessons from Protein Synthesis. Cell Volume 136, Issue 4, 20 February 2009, Pages 746-762PubMed ID19239893
Primary Source Zaher HS, Green R. Quality control by the ribosome following peptide bond formation. Nature. 2009 Jan 8457(7226):161-6.PubMed ID19092806
Method a well-defined in vitro bacterial translation system
Comments This increase in peptide release results in substantial losses in the fidelity of tRNA selection.
Entered by Uri M
ID 103486