Selection coefficient of cell hosting Tn5

Value 5 %
Organism Bacteria Escherichia coli
Reference Hartl DL, Dykhuizen DE. The population genetics of Escherichia coli. Annu Rev Genet. 1984 18: pp. 53PubMed ID6099090
Primary Source Biel SW, Hartl DL. Evolution of transposons: natural selection for Tn5 in Escherichia coli K12. Genetics. 1983 Apr103(4):585PubMed ID6303898
Method cell culture in chemostats and estimation of strain frequency
Comments The Tn5-bearing strain is in advantage-has a more rapid growth rate and increases in frequency from 50% to 90% within the first 15 to 20 generations compared to non Tn5 bearing strain
Entered by Uri M
ID 102555