Distribution of iron

Range bound to hemoglobin ~65%: bound to ferritin and hemosiderin ~25%: in oxygen carrier proteins ~10% %
Organism Human Homo sapiens
Reference Valko M et al., Redox- and non-redox-metal-induced formation of free radicals and their role in human disease. Arch Toxicol. 2016 Jan90(1):1-37. doi: 10.1007/s00204-015-1579-5 p.4 right column 4th paragraphPubMed ID26343967
Primary Source Winter WE, Bazydlo LA, Harris NS (2014) The molecular biology of human iron metabolism. Lab Med 45: 92–102. doi: 10.1309/ LMF28S2GIMXNWHMMPubMed ID24868988
Comments P.4 right column 4th paragraph: "Of the order of 65% of iron in living organisms is bound to the carrier protein hemoglobin, about 25% is bound to the iron-storage proteins ferritin and hemosiderin, and about 10% is an integral part of oxygen carrier proteins, myoglobin and cytochromes (primary source). Only a very small amount of iron is present in the form of a redox-active iron pool, sometimes termed as the labile iron pool (LIP), which represents iron bound to low-affinity intracellular low molecular weight ligands."
Entered by Uri M
ID 114059