Protein-protein interactions of key components of the Sec transport machinery

Range Table - link nM
Organism bacteria
Reference Kudva R, Denks K, Kuhn P, Vogt A, Müller M, Koch HG. Protein translocation across the inner membrane of Gram-negative bacteria: the Sec and Tat dependent protein transport pathways. Res Microbiol. 2013 Jul-Aug164(6):505-34. doi: 10.1016/j.resmic.2013.03.016 p.509 table 1PubMed ID23567322
Primary Source See pointers to refs in table
Comments P.509 left column 2nd paragraph: "The different oligomeric states of the SecYEG translocon that have been reported probably reflect substrate dependent dynamic and modular organisation of the SecYEG translocon. The modular organisation of the translocon is also supported by the number of proteins that have been found to interact at least transiently with the SecYEG translocon (Table 1, Fig. 3)." P.511 right column 2nd paragraph: "The affinity of SRP [signal recognition particle] for ribosome associated nascent chains (RNCs) varies between 0.5 and 1 nM for the SA [Signal Anchor] sequence of the membrane protein leader peptidase (Lep) (Table 1, Bornemann et al., 2008) and 80-100 nM for the cleavable signal sequence of the periplasmic protein alkaline phosphatase (Zhang et al., 2010)." See note above table
Entered by Uri M
ID 113761