Interspecies (human, rat, baboon) comparison of characteristics of cells from the alveolar region of normal lungs

Range Table - link
Organism Mammals
Reference Crapo JD, Barry BE, Gehr P, Bachofen M, Weibel ER. Cell number and cell characteristics of the normal human lung. Am Rev Respir Dis. 1982 Aug126(2):332-7. DOI: 10.1164/arrd.1982.126.2.332 p.336 table 4PubMed ID7103258
Primary Source [4] Crapo JD, Barry BE, Foscue HA, Shelburne J. Structural and biochemical changes in rat lungs occurring during exposures to lethal and adaptive doses of oxygen. Am Rev Respir Dis. 1980 Jul122(1):123-43. DOI: 10.1164/arrd.1980.122.1.123 [17] Hayatdavoudi G et al., Pulmonary injury in rats following continuous exposure to 60% O2 for 7 days. J Appl Physiol Respir Environ Exerc Physiol. 1981 Nov51(5):1220-31.PubMed ID7406333, 6457819
Method Abstract: "An interspecies comparison of characteristics of cells from the alveolar regions of normal lungs from humans, baboons, and rats showed that proportions of cells in the alveolar region and their average thickness, size, and surface areas were relatively constant."
Comments P.336 middle column 2nd paragraph: "The characteristics of cells in the alveolar region of normal lungs from humans can be compared with previously published data on baboons (primary source 17) and rats (primary source 4)(table 4). Several interesting species variations in characteristics and proportions of cells found in the alveolar region of the lung were detected. Macrophages were more common in the human lung, whereas endothelial cells represented a higher proportion of the cells present in rat lung. Average cell volume and average cell surface area covered were of the same order of magnitude for cells from each species, although human alveolar type II cells, endothelial cells, interstitial cells and macrophages tended to be larger than in those of subhuman primates and rats." Please note-contrary to note beneath table, neither refs 16 nor primary source 17 didn't seem to study baboons. See notes beneath table
Entered by Uri M
ID 113412