| Range |
>20 %
|
| Organism |
Microbes |
| Reference |
Reuveni S, Meilijson I, Kupiec M, Ruppin E, Tuller T. Genome-scale analysis of translation elongation with a ribosome flow model. PLoS Comput Biol. 2011 Sep7(9):e1002127. doi: 10.1371/journal.pcbi.1002127. p.2 left column top paragraphPubMed ID21909250
|
| Method |
p.11 right column top paragraph:"[Investigators] described a novel analysis of large scale genomic data by a predictor/model that is based on the physical and dynamical nature of gene translation. Given the copy numbers of the tRNA genes in the host genome, [investigators'] model, the RFM [Ribosomal Flow Model], is based only on
codon-bias. It can hence be applied when only the coding sequence
of a gene is available and without additional data or information." |
| Comments |
p.2 left column top paragraph:"In addition, [investigators] provide the first direct estimate for the effect of codon order on protein abundance, showing that in E. coli and S. cerevisiae it can solely account for more than 20% of the variation in
this quantity." |
| Entered by |
Uri M |
| ID |
111574 |