Typical nuclear surface area

Value 7.4 μm^2
Organism Budding yeast Saccharomyces cerevisiae
Reference Oeffinger M, Zenklusen D. To the pore and through the pore: a story of mRNA export kinetics. Biochim Biophys Acta. 2012 Jun1819(6):494-506. doi: 10.1016/j.bbagrm.2012.02.011. p.498 left column 2nd paragraphPubMed ID22387213
Comments "Cyro-EM studies in yeast have shown that a G1 cell nucleus contains about 90 NPCs (nuclear pore complexes)[ref 57]. Considering a typical nuclear surface area of 7.4 µm^2 and a diameter of an NPC of 100µm [units in error, should be nm], one can calculate that NPCs account for about 10% of the total surface of the inner nuclear membrane [ref 58]."
Entered by Uri M
ID 110671