| Range |
Table - link unitless
|
| Organism |
Rat Rattus norvegicus |
| Reference |
Hafner RP, Brand MD. Hypothyroidism in rats does not lower mitochondrial ADP/O and H+/O ratios. Biochem J. 1988 Mar 1 250(2):477-84. p.479 table 1PubMed ID2833245
|
| Method |
"H+/O ratios were measured by the oxygen-pulse
technique of Mitchell & Moyle (1967) in the presence of
NEM [N-ethylmaleimide] to inhibit rapid phosphate movement (Brand
et al., 1976b)." |
| Comments |
"H+/O ratios were measured under three sets of
conditions for rats that had been made hypothyroid by
treatment with PTU [6-n-propyl-2-thiouracil], and under one of these conditions
for rats made hypothyroid by parathyroid-thyroidectomy. A sample trace of an experiment performed at
37 °C is shown in Fig. 1. The results are summarized in
Table 1. There was no significant decrease in the H+/O
ratios in mitochondria from hypothyroid rats relative to
mitochondria from control rats under any of the three
conditions." See note above table |
| Entered by |
Uri M |
| ID |
110655 |