| Comments |
Abstract: "The analysis yields, as a by-product, a major revision of the current human catalogs, cutting the number of protein-coding genes to approximately 20,500." P.19429 left column 2nd paragraph: "The results have three important consequences. First, the analysis yields as a by-product a major revision to the human gene catalog, cutting the number of genes from ≈24,500 to ≈20,500. The revision eliminates few valid protein-coding genes while dramatically increasing specificity. Second, the analysis provides a scientifically valid methodology for evaluating future proposed additions
to the human gene catalog. Third, the analysis implies that the mammalian protein-coding genes have been largely stable, with relatively little invention of truly novel genes." For 19,735 protein-coding genes in C. elegans see BNID 101364 |