Fraction of epithelial cells in the crypt and villus that are enterocytes

Range in crypt ≤90%: in villus >95% % of epithelial cells
Organism Mouse Mus musculus
Reference Fan MZ, Stoll B, Jiang R, Burrin DG. Enterocyte digestive enzyme activity along the crypt-villus and longitudinal axes in the neonatal pig small intestine. J Anim Sci. 2001 Feb79(2):371-81. p.371 left columnPubMed ID11219446
Primary Source Cheng, H., and C. P. Leblond. 1974. Origin, differentiation and renewal of the four main epithelial cell types in the mouse small intestine. I. Columnar cell. Am. J. Anat. 141:461−480PubMed ID4440632
Comments P.371 left column:"Enterocytes constitute up to 90% of epithelial cells in the crypt and more than 95% of villus cells (primary source). Studies designed to identify the mechanisms that control the enterocyte differentiation have been largely confined to cell culture models, and this area of intestinal growth remains poorly understood (Hermiston et al., 1994)."
Entered by Uri M
ID 112182