Pace of replication fork

Range ~300 nts/sec
Organism Archaea Pyrococcus abyssi
Reference Rocha EP. The replication-related organization of bacterial genomes. Microbiology. 2004 Jun150(Pt 6):1609-27. p.1610 left column 2nd paragraphPubMed ID15184548
Primary Source Myllykallio, H. et al., (2000). Bacterial mode of replication with eukaryotic-like machinery in a hyperthermophilic archaeon. Science 288 , 2212–2215.PubMed ID10864870
Comments "In each replication fork, a complex with two DNA polymerases replicates the two DNA strands. The pace of the replication fork varies significantly between bacteria. For example, in E. coli the fork progresses at ~1000 nt/s ,in Pyrococcus abyssi at ~300 nt/s (primary source) and in Mycoplasma capricolum at ~100 nt/s (Seto & Miyata, 1998). Thus although the M. capricolum genome is seven times smaller than that of E. coli , it takes longer to be replicated."
Entered by Uri M
ID 110933