Transport rate of soluble proteins by slow component b (SCb) of axonal anterograde transport

Range 3 to 6 mm/day
Organism Unspecified
Reference Hoffman PN. A conditioning lesion induces changes in gene expression and axonal transport that enhance regeneration by increasing the intrinsic growth state of axons. Exp Neurol. 2010 May223(1):11-8. p.14 right column top paragraphPubMed ID19766119
Primary Source Lasek, R.J., Hoffman, P.N., 1976. The neuronal cytoskeleton, axonal transport and axonal growth. Cold Spring Harbor Conf. Cell Proliferation 3, 1021–1049. AND Lasek RJ, Garner JA, Brady ST. Axonal transport of the cytoplasmic matrix. J Cell Biol. 1984 Jul99(1 Pt 2):212s-221s. AND Filliatreau G, Denoulet P, de Nechaud B, Di Giamberardino L. Stable and metastable cytoskeletal polymers carried by slow axonal transport. J Neurosci. 1988 Jul8(7):2227-33. AND Tashiro T, Komiya Y. Stable and dynamic forms of cytoskeletal proteins in slow axonal transport. J Neurosci. 1989 Mar9(3):760-8.PubMed ID6378920, 3249221, 2926480
Comments 4th primary source studied rat sciatic nerve. For range of 1 to 10 mm/day see Scott 2011 PMID 21555071 p.441 left column bottom paragraph
Entered by Uri M
ID 106707