Estimated peak number of positive strands within one Poliovirus-infected cell

Value 76000 Copies/cell
Organism Poliovirus
Reference Thébaud G, Chadoeuf J, Morelli MJ, McCauley JW, Haydon DT. The relationship between mutation frequency and replication strategy in positive-sense single-stranded RNA viruses. Proc Biol Sci. 2010 Mar 7 277(1682):809-17PubMed ID19906671
Primary Source Novak JE, Kirkegaard K. Coupling between genome translation and replication in an RNA virus. Genes Dev. 1994 Jul 15 8(14):1726-37.PubMed ID7958852
Method Primary source- plaque assay of Wild type + R2 (helper RNA provided in trans) in supD12A cells.
Entered by Uri M
ID 105210