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Estimated peak number of positive strands within one Poliovirus-infected cell

Value	76000 Copies/cell
Organism	Poliovirus
Reference	Thébaud G, Chadoeuf J, Morelli MJ, McCauley JW, Haydon DT. The relationship between mutation frequency and replication strategy in positive-sense single-stranded RNA viruses. Proc Biol Sci. 2010 Mar 7 277(1682):809-17PubMed ID19906671
Primary Source	Novak JE, Kirkegaard K. Coupling between genome translation and replication in an RNA virus. Genes Dev. 1994 Jul 15 8(14):1726-37.PubMed ID7958852
Method	Primary source- plaque assay of Wild type + R2 (helper RNA provided in trans) in supD12A cells.
Entered by	Uri M
ID	105210