Percent of Langerhans cells lost from epidermis after 4 week alcohol consumption

Range 30-50 %
Organism Mouse Mus musculus
Reference Ness KJ, Fan J, Wilke WW, Coleman RA, Cook RT, Schlueter AJ.Chronic ethanol consumption decreases murine Langerhans cell numbers and delays migration of Langerhans cells as well as dermal dendritic cells. Alcohol Clin Exp Res. 2008 Apr32(4):pp. 665, pp.660 fig. 1PubMed ID18241312
Method Baseline Langerhans cell (LC) and dermal DC (dDC) numbers were enumerated by immunofluorescence (IF).
Comments Inspite of low LC cells in epidermis there was persistent maintenance of the dDC population in the presence of up to 16 weeks of EtOH
Entered by Uri M
ID 102640