Fraction of pregnancies in which fetal membranes will rupture before the onset of labor

Range ~8 - 10 %
Organism Human Homo sapiens
Reference Cools P. The role of Escherichia coli in reproductive health: state of the art. Res Microbiol. 2017 Feb 24. pii: S0923-2508(17)30037-2. doi: 10.1016/j.resmic.2017.02.002. p.2 right column bottom paragraphPubMed ID28242352
Primary Source [22] A.B. Caughey, J.N. Robinson, E.R. Norwitz, Contemporary diagnosis and management of preterm premature rupture of membranes, Rev Obstet Gynecol, 1 (2008), pp. 11–22PubMed ID18701929
Comments P.2 right column bottom paragraph: "In approximately 8–10% of pregnancies, fetal membranes will rupture before the onset of labor [primary source]. When this occurs at 37 weeks or later, this premature rupture of the membranes (PROM) is an easy-to-manage complication of a normal birth. PROM occurring before 37 weeks is defined as preterm premature rupture of membranes (PPROM) [ref 41], and is rarer. PPROM is difficult to manage and responsible for as many as 20% of perinatal deaths [primary source]. In most PPROM cases, the cause is unknown, but (subclinical) intrauterine infection is a frequent precursor [refs 41, 81]. Since the fetal membranes generally form a barrier to ascending infection, intrauterine infections and preterm labor are also common complications of PPROM [refs 41, 40]."
Entered by Uri M
ID 113488