Average duration of short bursts of mRNA production & long periods of inactivity between bursts

Range bursts of mRNA production 6min: periods between bursts 37min min
Organism Bacteria Escherichia coli
Reference Li GW, Xie XS. Central dogma at the single-molecule level in living cells. Nature. 2011 Jul 20 475(7356):308-15. doi: 10.1038/nature10315. p.313 cation of fig.5d and p.312 right column top paragraphPubMed ID21776076
Primary Source Golding, I., Paulsson, J., Zawilski, S. M. & Cox, E. C. Real-time kinetics of gene activity in individual bacteria. Cell 123, 1025–1036 (2005).PubMed ID16360033
Method "Advanced single-cell fluorescence microscopy"
Comments P.312 right column top paragraph: "Surprisingly, short bursts (average 6 min) of mRNA synthesis followed by long periods (average 37 min) of inactivity have been observed [primary source]." Keywords:gene expression,transcription factor,central dogma
Entered by Uri M
ID 112109