Fraction of total protein mass that is cytosolic chaperone HSPA8 (HSC70)

Range ≤1 %
Organism Eukaryotes
Reference Finka A, Sood V, Quadroni M, Rios PL, Goloubinoff P. Quantitative proteomics of heat-treated human cells show an across-the-board mild depletion of housekeeping proteins to massively accumulate few HSPs. Cell Stress Chaperones. 2015 Apr 8. doi 10.1007/s12192-015-0583-2 p.2/16 left column bottom paragraphPubMed ID25847399
Primary Source Finka A, Goloubinoff P (2014) The CNGCb and CNGCd genes from Physcomitrella patens moss encode for thermosensory calcium channels responding to fluidity changes in the plasma membrane. Cell Stress Chaperones 19: 83–90. doi:10.?1007/?s12192-013-0436-9PubMed ID23666745
Comments p.2/16 left column bottom paragraph:"Thus, the cytosolic chaperone HSPA8 (HSC70) (primary source), which can be as much as 1 % of the total protein mass in eukaryotes, is generally thought to be evenly expressed under stress and physiological conditions."
Entered by Uri M
ID 111538