Number of secretory granules in β cells

Range ~10,000 granules/β cell
Organism Human Homo sapiens
Reference Rorsman P, Braun M. Regulation of insulin secretion in human pancreatic islets. Annu Rev Physiol. 2013 75 :155-79. doi: 10.1146/annurev-physiol-030212-183754. p.167 3rd paragraphPubMed ID22974438
Primary Source Rosengren AH, BraunM,Mahdi T, Andersson SA, TraversME, et al. 2012. Reduced insulin exocytosis in human pancreatic ß-cells with gene variants linked to type 2 diabetes. Diabetes 61: 1726–33PubMed ID22492527
Comments "Human ß cells contain ~10,000 secretory granules (primary source)."
Entered by Uri M
ID 109971