Total cellular protein concentration

Range ~250 mg/ml
Organism Bacteria Leptospira interrogans
Reference Malmström J, Beck M, Schmidt A, Lange V, Deutsch EW, Aebersold R. Proteome-wide cellular protein concentrations of the human pathogen Leptospira interrogans. Nature. 2009 Aug 6 460(7256):762-5 p.763 right column bottom paragraphPubMed ID19606093
Method On the basis of the proteome-wide absolute abundance data and the cell volume measurements by cryoET, researchers determined the total cellular protein concentration to be ~250 mg/ml by summing all protein copies and dividing by the volume. This protein concentration is in agreement with earlier studies in Escherichia coli (ref 19).
Entered by Uri M
ID 108015