Number of different protein post-translational modifications
| Value | 300 Unitless |
|---|---|
| Organism | Human Homo sapiens |
| Reference | Morón JA, Devi LA. Use of proteomics for the identification of novel drug targets in brain diseases. J Neurochem. 2007 Jul102(2):306-15PubMed ID17419802 |
| Primary Source | Aebersold R, Goodlett DR. Mass spectrometry in proteomics. Chem Rev. 2001 Feb101(2):269-95PubMed ID11712248 |
| Comments | In total, there are approximately 300 different PTM that have been reported (Aebersold and Goodlett 2001), affecting protein conformation, stability, localization, binding interactions, and function. The majority of proteins are modified after translation, often at more than one site. In most cases, the sites of modification are not predictable from the amino acid sequence. |
| Entered by | Uri M |
| ID | 104522 |