Diffusion coefficient of protamine in p(HEMA-DMAEMA) hydrogel when loaded by entrapment

Value 33 um^2/sec
Organism Unspecified
Reference Brahim S, Narinesingh D, Guiseppi-Elie A. Release characteristics of novel pH-sensitive p(HEMA-DMAEMA) hydrogels containing 3-(trimethoxy-silyl) propyl methacrylate. Biomacromolecules. 2003 Sep-Oct4(5):1224-31PubMed ID12959587
Method An amphiphilic hydrogel of poly(2-hydroxyethyl methacrylate) cross-linked with tetraethyleneglycol diacrylate (TEGDA) was synthesized to contain the hydrophobic monomer 3-(trimethoxy-silyl) propyl methacrylate (PMA) and the pH-responsive, hydrophilic monomer N',N'-dimethylaminoethyl methacrylate (DMAEMA).
Comments For gels loaded by physical entrapment, the quantity of each biomolecule was determined from the difference between amounts offered to the monomeric solution prior to polymerization and the amount found in the wash solution after gel formation. The results of this study are summarized in Table 1.
Entered by Uri M
ID 104041