Regeneration of drastic lesions that ablate large portions of the pallium (in the cerebrum in the brain)

Range ≤12-15 weeks
Organism Salamander axolotl Ambystoma mexicanum
Reference Alunni A, Bally-Cuif L. A comparative view of regenerative neurogenesis in vertebrates. Development. 2016 Mar 1 143(5):741-53. doi: 10.1242/dev.122796 p.745 right column bottom paragraphPubMed ID26932669
Primary Source Maden M, Manwell LA, Ormerod BK. Proliferation zones in the axolotl brain and regeneration of the telencephalon. Neural Dev. 2013 Jan 17 8: 1. doi: 10.1186/1749-8104-8-1PubMed ID23327114
Method BrdU labeling and Immunocytochemistry
Comments P.745 right column bottom paragraph: "Regeneration assays in the axolotl brain usually involve drastic lesions that ablate large portions of the pallium. These lesions regenerate within 12-15 weeks, but only when the olfactory nerve is preserved, or after it has regrown to re-establish contact with telencephalic tissue (primary source)."
Entered by Uri M
ID 117246