Fraction of all neurons that are produced in embryonic NB (neuroblast) divisions

Range of larval central nervous system (CNS) 100%: of adult CNS 10% % of cells
Organism Fruit fly Drosophila melanogaster
Reference Homem CC, Knoblich JA. Drosophila neuroblasts: a model for stem cell biology. Development. 2012 Dec 1 139(23):4297-310. doi: 10.1242/dev.080515 p.4297 right column 3rd paragraphPubMed ID23132240
Primary Source Prokop A, Technau GM. The origin of postembryonic neuroblasts in the ventral nerve cord of Drosophila melanogaster. Development. 1991 Jan111(1):79-88 AND Green P, Hartenstein AY, Hartenstein V. The embryonic development of the Drosophila visual system. Cell Tissue Res. 1993 Sep273(3):583-98 DOI: 10.1007/bf00333712PubMed ID1901786, 8402833
Method Primary source Green et al., abstract: "[Investigators] have used electron-microscopic studies, bromodeoxyuridine (BrdU) incorporation and antibody labeling to characterize the development of the Drosophila larval photoreceptor (or Bolwig's) organ and the optic lobe, and have investigated the role of Notch in the development of both."
Comments P.4297 right column 3rd paragraph: "Embryonic NB divisions produce all the neurons that will form the larval central nervous system (CNS) but only 10% of the cells in the adult CNS (primary sources)."
Entered by Uri M
ID 117236