Rough number of CA3 (Cornu Ammonis region 3 (in hippocampus)) pyramidal neurons each dentate gyrus granule cell contacts with

Range 10-15 CA3 pyramidal neurons
Organism Rat Rattus norvegicus
Reference Josselyn SA, Frankland PW. Infantile amnesia: a neurogenic hypothesis. Learn Mem. 2012 Aug 16 19(9):423-33. doi: 10.1101/lm.021311.110 p.428 right column 2nd paragraphPubMed ID22904373
Primary Source Acsády L, Kamondi A, Sík A, Freund T, Buzsáki G. GABAergic cells are the major postsynaptic targets of mossy fibers in the rat hippocampus. J Neurosci. 1998 May 1 18(9):3386-403PubMed ID9547246
Method Primary source abstract: "[Investigators] examined the postsynaptic targets of mossy fibers by combining in vivo intracellular labeling of granule cells, immunocytochemistry, and electron microscopy."
Comments P.428 right column 2nd paragraph: "Each dentate granule cell contacts roughly 10–15 CA3 pyramidal neurons via large mossy fiber terminals (primary source)." Primary source abstract: "Single granule cells formed large, complex "mossy" synapses on 11-15 CA3 pyramidal cells and 7-12 hilar mossy cells."
Entered by Uri M
ID 117232