Oxygen concentration in cerebral circulation

Range in fetuses (in utero) 25-30: shortly after premature birth 50-60 mmHg
Organism Human Homo sapiens
Reference Malik S et al., Neurogenesis continues in the third trimester of pregnancy and is suppressed by premature birth. J Neurosci. 2013 Jan 9 33(2):411-23. doi: 10.1523/JNEUROSCI.4445-12.2013 p.412 left column 2nd paragraphPubMed ID23303921
Primary Source Soothill PW, Nicolaides KH, Rodeck CH, Gamsu H. Blood gases and acid-base status of the human second-trimester fetus. Obstet Gynecol. 1986 Aug68(2):173-6PubMed ID3090491
Method Primary source abstract: "Maternal arterial, umbilical venous, and umbilical arterial blood were obtained at fetoscopy in the second trimester and analyzed for blood gases and acid-base indexes."
Comments P.412 left column 2nd paragraph: "Neurogenesis is temporally regulated, and premature birth might affect it. Oxygen is a key regulator of neurogenesis (Panchision, 2009). Oxygen concentration in cerebral circulation is 25–30 mmHg in fetuses (in utero), which increases to 50–60 mmHg shortly after premature birth (primary souurce)."
Entered by Uri M
ID 117217