| Range |
Table - link
|
| Organism |
Vertebrates |
| Reference |
Tepper JM et al., Heterogeneity and Diversity of Striatal GABAergic Interneurons: Update 2018. Front Neuroanat. 2018 Nov 8 12: 91. doi: 10.3389/fnana.2018.00091 p.11 table 1PubMed ID30467465
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| Method |
Abstract: "In this review, [investigators] report on further advances in the understanding of the functional properties of previously reported striatal GABAergic interneurons and their synaptic connections. With the application of new transgenic fluorescent reporter and Cre-driver/reporter lines, plus optogenetic, chemogenetic and viral transduction methods, several additional subtypes of novel striatal GABAergic interneurons have been discovered, as well as the synaptic networks in which they are embedded." |
| Comments |
P.6 right column 6th paragraph: "Probably the most novel characteristic of the SABIs [spontaneously active bursty interneurons] is that unlike all other striatal GABAergic interneurons identified to date, they do not significantly innervate SPNs [spiny projection neurons]. Using paired-recording in slices [investigators] found only 2 out of 45 connected pairs between nearby SABI and SPNs (4.4%: Table 1). Similarly, [they] observed the same very low connection probability in paired recordings when the SPNs were tested as presynaptic to SABIs (1 out of 24: 4.1%). These observations suggest that the principal synaptic targets of SABIs are other striatal interneurons." See abbreviations beneath table |
| Entered by |
Uri M |
| ID |
117207 |