Size of receptive field of (retinal) horizontal cells

Value 25 times the size of an individual cell's dendritic arbor
Organism Vertebrates
Reference Bloomfield SA, Völgyi B. The diverse functional roles and regulation of neuronal gap junctions in the retina. Nat Rev Neurosci. 2009 Jul10(7):495-506 doi: 10.1038/nrn2636 p.500 left column 3rd paragraphPubMed ID19491906
Primary Source [81] Bloomfield SA, Xin D, Persky SE. A comparison of receptive field and tracer coupling size of horizontal cells in the rabbit retina. Vis Neurosci. 1995 Sep-Oct12(5):985-99 [84] Naka KI, Rushton WA. The generation and spread of S-potentials in fish (Cyprinidae). J Physiol. 1967 Sep192(2):437-61 DOI: 10.1113/jphysiol.1967.sp008308 [85] Bloomfield SA, Miller RF. A physiological and morphological study of the horizontal cell types of the rabbit retina. J Comp Neurol. 1982 Jul 1 208(3):288-303 DOI: 10.1002/cne.902080306PubMed ID8924420, 6050157, 6288777
Method Primary source [81] abstract: "[Investigators] studied this question [that the pattern of tracer coupling may provide some index of the extent of electrical coupling] by comparing the receptive field and tracer coupling size of dark-adapted horizontal cells recorded in the superfused, isolated retina-eyecup of the rabbit. Both the edge-to-edge receptive field and space constants (lambda) were computed for each cell using a long, narrow slit of light displaced across the retinal surface. Cells were subsequently labeled by iontophoretic injection of Neurobiotin." Primary source [84] abstract: "S-potentials from Luminosity-units in the excised eye of the tench (Tinca) were excited by white lights of various intensities and spatial distributions." Primary source [85] abstract: "A perfused, isolated retina-eyecup preparation of the rabbit was utilized to correlate the physiology and morphology of horizontal cells. Neurons were physiologically characterized by intracellular recording techniques and subsequently stained with intracellular iontophoretically injected horseradish peroxidase for morphological identification. Three types of rabbit horizontal cell recordings have been differentiated, based on variations in response waveform, amplitude-intensity properties, and area summation characteristics."
Comments P.500 left column 3rd paragraph: "The extensive gap junctional coupling between horizontal cells results in their characteristically large receptive fields, which can be 25 times the size of an individual cell's dendritic arbor (primary sources 81, 84, 85). This indicates an extremely efficient lateral spread of visual signals through electrical synapses (primary source 81)." Primary sources [81] and [85] studied rabbits. Primary source [84] studied tench (Tinca tinca), a fish
Entered by Uri M
ID 117169