| Value |
150
µsec
|
| Organism |
Rat Rattus norvegicus |
| Reference |
Connors BW, Long MA. Electrical synapses in the mammalian brain. Annu Rev Neurosci. 2004 27: 393-418 DOI: 10.1146/annurev.neuro.26.041002.131128 p.409 2nd paragraphPubMed ID15217338
|
| Primary Source |
Sabatini BL, Regehr WG. Timing of neurotransmission at fast synapses in the mammalian brain. Nature. 1996 Nov 14 384(6605):170-2 DOI: 10.1038/384170a0PubMed ID8906792
|
| Method |
Primary source abstract: "[Investigators] have developed a new approach to study timing at rat cerebellar synapses: [they] used optical techniques to measure voltage and calcium current simultaneously from presynaptic boutons while monitoring postsynaptic currents electrically." |
| Comments |
P.409 2nd paragraph: "Electrical synapses are faster than chemical synapses, but this advantage is minimized at mammalian body temperatures, where chemical synaptic delays are only 150 μsec (primary source)." Primary source abstract: "Here [investigators] report that the classic view that vesicle release is driven by calcium entry during action-potential repolarization holds for these synapses at room temperature, but not at physiological temperatures, where postsynaptic responses commence just 150 μs after the start of the presynaptic action potential." |
| Entered by |
Uri M |
| ID |
117167 |