| Range |
0.7 - 1.6 nS
|
| Organism |
Rat Rattus norvegicus |
| Reference |
Connors BW, Long MA. Electrical synapses in the mammalian brain. Annu Rev Neurosci. 2004 27: 393-418 DOI: 10.1146/annurev.neuro.26.041002.131128 p.405 2nd paragraphPubMed ID15217338
|
| Primary Source |
Galarreta M, Hestrin S. A network of fast-spiking cells in the neocortex connected by electrical synapses. Nature. 1999 Nov 4 402(6757):72-5 DOI: 10.1038/47029 AND Gibson JR, Beierlein M, Connors BW. Two networks of electrically coupled inhibitory neurons in neocortex. Nature. 1999 Nov 4 402(6757):75-9 DOI: 10.1038/47035PubMed ID10573418, 10573419
|
| Method |
Primary source Galarreta & Hestrin abstract: "Encoding of information in the cortex is thought to depend on synchronous firing of cortical neurons. Inhibitory neurons are known to be critical in the coordination of cortical activity, but how interaction among inhibitory cells promotes synchrony is not well understood. To address this issue directly, [investigators] have recorded simultaneously from pairs of fast-spiking (FS) cells, a type of gamma-aminobutyric acid (GABA)-containing neocortical interneuron." Primary source Gibson et al. abstract: "Here [investigators] describe two functionally distinct inhibitory networks comprising either fast-spiking (FS) or low-threshold spiking (LTS) neurons. Paired-cell recordings showed that inhibitory neurons of the same type were strongly interconnected by electrical synapses, but electrical synapses between different inhibitory cell types were rare." |
| Comments |
P.405 2nd paragraph: "Immature (2–3 weeks of age) rat neocortical interneurons are more strongly coupled, with a mean estimated junctional conductances of 0.7–1.6 nS (primary sources), but the size of their gap junctions is unknown." |
| Entered by |
Uri M |
| ID |
117166 |