Fraction of the time that the late-spiking (LS) inhibitory interneuron made electrical synapses to other LS cells in layer I of the neocortex

Value 83 % of the time
Organism Rat Rattus norvegicus
Reference Connors BW, Long MA. Electrical synapses in the mammalian brain. Annu Rev Neurosci. 2004 27: 393-418 DOI: 10.1146/annurev.neuro.26.041002.131128 p.402 top paragraphPubMed ID15217338
Primary Source Chu Z, Galarreta M, Hestrin S. Synaptic interactions of late-spiking neocortical neurons in layer 1. J Neurosci. 2003 Jan 1 23(1):96-102PubMed ID12514205
Method Primary source abstract: "[Investigators] studied the physiological properties and synaptic interactions of a class of cells within layer 1 called late-spiking (LS) cells... Using paired recording, [they] showed that LS cells formed GABAergic connections with other LS cells as well as with non-LS cells in layer 1 and with pyramidal cells in layer 2/3."
Comments P.402 top paragraph: "In layer I of the neocortex, the late-spiking (LS) inhibitory interneuron made electrical synapses to other LS cells 83% of the time, but it coupled to non-LS interneurons only 2% of the time (primary source)." Primary source abstract: "It has been suggested previously that GABAergic neurons belonging to the same class in the cortex are electrically coupled. In agreement with that hypothesis, [investigators] found that LS cells were interconnected by electrical coupling (83%), whereas electrical coupling between LS cells and non-LS cells was infrequent (2%)."
Entered by Uri M
ID 117161