Glutamate concentration

Range in interstitial fluid (ISF) <1: in plasma ~100 µM
Organism Unspecified
Reference Abbott NJ, Rönnbäck L, Hansson E. Astrocyte-endothelial interactions at the blood-brain barrier. Nat Rev Neurosci. 2006 Jan7(1):41-53 DOI: 10.1038/nrn1824 p.44 right column top paragraphPubMed ID16371949
Comments P.44 right column top paragraph: "They (efflux transporters) include several Na+-dependent glutamate transporters (excitatory amino acid transporters 1–3: EAAT1–3)(ref 27), which move glutamate out of the brain against the large opposing concentration gradient (<1 μM in ISF compared with ∼100 μM in plasma) (Fig. 2)."
Entered by Uri M
ID 117114