| Range |
rarely >8–20 µm
|
| Organism |
Rat Rattus norvegicus |
| Reference |
Abbott NJ, Rönnbäck L, Hansson E. Astrocyte-endothelial interactions at the blood-brain barrier. Nat Rev Neurosci. 2006 Jan7(1):41-53 DOI: 10.1038/nrn1824 p.41 right column top paragraphPubMed ID16371949
|
| Primary Source |
[6] Schlageter KE, Molnar P, Lapin GD, Groothuis DR. Microvessel organization and structure in experimental brain tumors: microvessel populations with distinctive structural and functional properties. Microvasc Res. 1999 Nov58(3):312-28 DOI: 10.1006/mvre.1999.2188PubMed ID10527772
|
| Method |
Primary source abstract: "[Investigators] studied microvessel organization in five brain tumor models (ENU, MSV, RG-2, S635cl15, and D-54MG) and normal brain, including microvessel diameter (LMVD), intermicrovessel distance (IMVD), microvessel density (MVD), surface area (S(v)), and orientation. LMVD and IMVD were larger and MVD was lower in tumors than normal brain...ENU and RG-2 tumors and brain were studied by electron microscopy." |
| Comments |
P.41 right column top paragraph: "Individual neurons are rarely more than 8–20 μm from a brain capillary (primary source), although they may be millimetres or centimetres from a CSF [Cerebrospinal fluid] compartment. Hence, of the various CNS [central nervous system] barriers, the BBB [blood-brain barrier] exerts the greatest control over the immediate microenvironment of brain cells." |
| Entered by |
Uri M |
| ID |
117110 |